Tag: Gut microbiome
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The Gut-Brain Axis and Microbial Biofilm-Associated Proteins: Driving Neurodegeneration in Parkinson’s
Parkinson’s disease pathology is increasingly linked to the gut-brain axis, with alpha-synuclein aggregation believed to originate in the enteric nervous system and spread to the brain. Gut microbiome dysbiosis and its biofilm-associated proteins (BAPs) act as “transmissible catalysts” that initiate and propagate this neurodegeneration through cross-seeding.